Endocrine Abstracts

Introduction: Hypothyroidism is a very common condition, and its treatment is relatively easy with levothyroxine (LT4). However, cases of resistant hypothyroidism were reported despite high doses of levothyroxine. The aim of this study was to evaluate the usefulness of the levothyroxine absorption test to confirm or exclude a disorder of thyroid hormone absorption.Methods: This was a retrospective study including patients who were admitted to our departm...

Introduction: Acromegaly is a rare endocrine disorder. In 95% of cases, it is caused by a GH-secreting pituitary adenoma. Rarely, acromegaly is due to ectopic production of GH or growth hormone-releasing hormone (GHRH). Herein, we report a case of acromegaly with negative pituitary magnetic resonance imaging (MRI) and discuss its possible etiology and management.Observation: A 75-year-old woman was referred to our department for the exploration of acquir...

Introduction: Ectopic thyroid gland is a rare pathology due to an abnormality in the embryological development and/or migration of the gland. The aim of this study was to assess clinical and paraclinical characteristics of adult patients with ectopic thyroid gland.Methods: This was a retrospective study including adult patients with ectopic thyroid gland. Clinical, biological, hormonal, radiological and therapeutic data were collected.<p class="abste...

Introduction: Growth retardation in sickle cell children is common and multifactorial. Recent evidence suggests damage to the somatotropic axis. We report the case of a patient followed for homozygous sickle cell anemia and in whom we discover an associated GH deficiency.Observation: It is a 13 year old child followed for homozygous sickle cell anemia, splenectomized for 2 years, not polytransfused. We were sent to the hematology department before a dela...

Background: Pituitary gland metastasis is rarely the initial presentation of metastatic cancer. Most cases of pituitary gland metastasis are asymptomatic with diabetes insipidus being the most common symptomatic presentation. It can rarely present with symptoms of hormone underproduction such as anterior pituitary deficiency. Although pituitary gland metastasis is rare, it is underestimated, as it is commonly misdiagnosed with pituitary gland adenoma due to the lack of clear r...

Introduction: Glycaemic control is still difficult to achieve despite advances in the pharmacotherapy of type 2 diabetes. Moreover, the COVID-19 crisis led to a disruption in medical consultations and in the access to medications. The aim of our study was to identify factors associated with poor glycaemic control in Tunisian type 2 diabetic patients during the COVID-19 crisis.Methods: This is a cross-sectional study, carried out in December 2021, on type...

Introduction: Chronic hyperglycemia in type 2 diabetic patients is associated with an increased risk of micro and macrovascular complications. Therefore, glycemic control is the cornerstone of its management. The aim of this study was to evaluate glycemic control in patients with type 2 diabetes before and during COVID-19 crisis.Methods: A cross-sectional study was conducted during December 2021, in the outpatient clinic of the department of endocrinolog...

Introduction: Pallister-Hall syndrome (PHS) is a very rare congenital syndrome, and its exact prevalence is still unknown. The clinical diagnosis is usually made when a hypothalamic hamartoma is associated with polydactyly. Endocrine manifestations consist of hypopituitarism, hypopituitarism, which can affect one or more pituitary axes, and precocious puberty. Here, we report the case of an 18-year-old young man in whom the diagnosis of PHS was delayed until his hospitalizatio...

Introduction: The clinical presentation of a secretory pituitary macroadenoma usually consists of a tumor syndrome accompanied by visual disturbances with signs of pituitary insufficiency and/or hormonal hypersecretion. Herein we describe an unusual presentation of a mixed secretory adenoma.Observation: A 69-year-old was referred to our department for the management of a pituitary macroadenoma revealed by a symptomatology mimicking the Hakim Adams triad ...

Introduction: Factitious hypoglycaemia in adults is usually due to exogenous intake of insulin or hypoglycaemia sulfonamides. This occult intake is most often voluntary and the diagnosis is not always obvious.Observation: We report the case of a 37-year-old pregnant woman at 15 weeks of amenorrhoea, followed for addisson’s disease since 3 years and not diabetic, was referred to our department for acute adrenal insufficiency following the discontinua...